The Jacksonville Jaguars are the only winless team playing during the Week 5 NFL schedule, but they are 2.5-point favorites against the Colts in the latest Week 5 NFL odds, up from 1.5 from the opener. Jacksonville’s offense hasn’t scored more than 20 points in a game this season and is coming off back-to-back road losses. Indianapolis notched consecutive wins over the Bruins and Steelers to stay in contention with Houston atop the AFC South standings. Should you include both sides of that game in your Week 5 NFL picks?
Meanwhile, Kansas City is the only undefeated team remaining in the AFC after road wins over the Falcons and Chargers. The Chiefs are five-point favorites at home against the Saints on Monday Night Football in the Week 5 NFL odds, so Patrick Mahomes, Travis Kelce, and company could be popular Week 5 NFL betting picks. Before you make any Week 5 NFL picks or NFL picks, be sure to see the NFL predictions and betting tips from SportsLine’s proven computer model.
The model, which simulates each NFL game 10,000 times, rises well above $7,000 for $100 players on top rated. NFL picks since its inception. The model enters Week 5 of the 2024 NFL season on an incredible 188-131 run on top-rated NFL picks dating back to the 2017 season. It is also on a 42-23 list in top-rated NFL picks since Week 7 of 2022.
The model has also ranked in the top 10 on NFLPickWatch four of the past six years on straight NFL picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who followed it is way up.
Now, the model searched the Week 5 NFL odds and locked in five confident NFL best bets. If you successfully talk its picks, you’d be looking at a massive payout of around 25-1. You can only see the Week 5 NFL draft picks at SportsLine.
Top Weeks 5 NFL picks
After simulating each game 10,000 times, the model is high on the Buffalo Bills (-1, 47.5) to cover on the road against the Houston Texans. Buffalo found itself in an early hole at Baltimore in Week 4 and was unable to recover, suffering its first loss of the season. The Bills are still the second highest scoring team in the NFL though, surpassing the 30-point mark in wins over the Cardinals, Dolphins and Jaguars.
Bills quarterback Josh Allen threw for 814 yards and seven touchdowns while rushing for 106 yards and two more scores. The Texans rank in the bottom half of the league in scoring offense, so they will have trouble matching Allen blow for blow on Sunday. SportsLine’s model has Houston barely cracking the 20-point mark in this matchup, as Buffalo covers the spread in well over 50% of simulations. See what other NFL picks to make here.
How to make Week 5 NFL speeches
The model also jumped on four other NFL games where it says the line is very far, including multiple teams winning by more than double the spread, challenging punters everywhere. You can only see the best NFL Week 5 bets from the model and talk at SportsLine.
What are the model’s top Week 5 NFL picks, and which NFL matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the Week 5 NFL best bets from a 188-131 model run of top-rated picks.and find out.
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