NFL fans will be treated to several star-studded showdowns in Week 1. The Week 1 NFL schedule is loaded with matchups that oddsmakers predict will be tough battles. Of the 16 NFL games in Week 1, only one has a spread higher than seven points, with the Bengals favored by 8.5 over the Patriots according to the latest Week 1 NFL odds. There are 13 games in the Week 1 NFL lineups that feature NFL spreads lower than five points, which could make your Week 1 NFL picks a serious challenge.
One of the marquee matchups on the Week 1 NFL schedule is Rams vs. Lions. Detroit is favored by 3.5 at home, but should you include the Lions in your Week 1 NFL betting strategy? Before you make any Week 1 NFL picks, you must see the NFL vs. the spread, over-under and moneyline predictions powered by SportsLine AI.
Built with cutting-edge artificial intelligence and machine learning techniques from the SportsLine Data Team, AI Predictions and AI Scores are generated for every game. The AI predictions are determined by statistically learning the historical data of each team and then quantitatively evaluating the strength of the opponent’s defense by assigning a numerical value out of 100 called a match score.
Once a forecast is formulated, the AI rating is generated using the forecast, the competition score and the odds of the market. For example, you might see an A rating on an over bet if a team faces a bad defense, their prediction differs from the line and there are favorable odds.
In addition, SportsLine AI is the first fully automated forecasting model at SportsLine. It continuously refreshes the most recent data available and can help you spot the biggest differences in the lines. Last season, SportsLine’s AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who followed it is way up.
For Week 1, the AI PickBot estimated NFL odds and provided NFL predictions for all 16 games. You can only see the AI predictions for the Week 1 NFL schedule here.
NFL AI’s top Week 1 picks
After analyzing every game in Week 1, the AI PickBot says the Broncos cover as six-point underdogs against the Seahawks in a game that earned an A-rated pick. The Broncos have announced that rookie quarterback Bo Nix will be the starter when Denver takes the field on Sunday afternoon. Nix had a stellar college career, passing for 4,508 yards, 45 touchdowns and just three interceptions last season at Oregon.
Nix beat out both Zach Wilson and Jarrett Stidham in camp, and he showed flashes of brilliance in the preseason. He completed eight of nine passes for 80 yards and a touchdown in Denver’s preseason win over Green Bay. The Broncos have also fared well against the Seahawks over the years, winning 13 of the last 19 meetings with Seattle. In addition, the Seahawks lost five of their final eight games to finish the season at 9-8 and miss the playoffs, which is a big reason why the AI PickBot favors taking the points with Denver in Week 1. See its other soccer predictions and soccer picks at SportsLine.
How to make Week 1 NFL picks
In addition, the AI PickBot generated eight more A-rated picks for Week 1. You must view the AI PickBot’s analysis before placing any Week 1 NFL bets. You can only see it on SportsLine.
Who wins and covers every Week 1 NFL game, and which picks should you target? Visit SportsLine now to see the best NFL picks against the spread, over-under and money line, all from the all-new SportsLine AI PickBot, which nailed 1,674 top-rated picks last season..
