The Kansas City Chiefs will try to bounce back from a loss for the first time since 2023 when they face the Carolina Panthers on Sunday during the Week 12 NFL schedule. Kansas City had its 15-game winning streak and bid for a perfect season marred in a 30-21 loss to Buffalo in an AFC showdown last week. The Chiefs are 11-point road favorites at Carolina in the Week 12 NFL odds, with an over-under of 43, despite the Panthers entering with an extra week of rest and a two-game winning streak. Should you back the Panthers as double-digit underdogs with your Week 12 NFL picks and best NFL bets?
Washington is also a double-digit favorite this week, listed at -10.5 against Dallas in the Week 12 NFL Vegas odds, with an over-under of 45. The Commanders are on a two-game losing streak and were swept by the Cowboys last time. season, so there could be an argument for dropping Washington with your Week 12 NFL predictions. The Cowboys will once again be without quarterback Dak Prescott, who is out for the year with a hamstring injury. Before you make any Week 12 NFL picks or NFL picks, be sure see the NFL predictions and betting tips from SportsLine’s proven computer model.
The model, which simulates each NFL game 10,000 times, raises well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 12 of the 2024 NFL season on an incredible 20-8 betting hot streak on top-rated. NFL picks this year. Longer term, it’s on a 200-136 list on top-rated NFL picks dating back to the 2017 season and a 54-29 roll on top-rated NFL picks since Week 7 of 2022.
The model has also ranked in the top 10 on NFLPickWatch four of the past six years on straight NFL picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who follows sportsbooks and betting apps has seen strong returns.
Now, the model searched the Week 12 NFL odds and locked in five confident NFL best bets. If you successfully use its sports betting options, you would be looking at a massive payout of around 25-1. You can only see the model’s Week 12 NFL picks at SportsLine.
Top Week 12 NFL picks
After simulating each game 10,000 times, the model is high on the Detroit Lions (-7.5, 50.5) to cover against the Indianapolis Colts. Detroit was the heaviest favorite of any team in the league this season when it closed as a 13.5-point favorite against Jacksonville last week, but the Lions had no problem covering that number in a 52-6 victory. Their 46-point scoring margin was the largest in franchise history, and their 645 total yards was also a franchise record.
They won eight straight games and nine of their first 10 games, becoming the third team in the Super Bowl era to win three of their first 10 games by at least 35 points. Detroit’s offense is averaging a whopping 33.6 points per game, which will cause problems for an Indianapolis offense that is scoring just 21.5 points per game. The Lions have covered the spread in seven of their last eight games, and the model has them covering more than 50% of simulations. See what other NFL picks to make here.
How to make Week 12 NFL speeches
The model also jumped on four other NFL games where it says the line is way off, including an underdog who wins outright. You can only see the best Week 12 NFL bets and NFL talk at SportsLine.
What are the model’s top Week 12 NFL picks, and which NFL matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the best NFL Week 12 bets from a 200-136 run model on top rated picks, and find out.
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